The White Sox have become a fan-favorite team so far in the playoffs and they look to keep rolling in Game 2. 

Gavin Williams gets the ball for the Guardians on Monday, while Chicago goes with an opener for this must-win Game 2.

The oddsmakers and bettors hate openers from a betting perspective, with Chicago coming in as big +141 underdogs on FanDuel.

It’s the second biggest underdog we’ve seen this round of the playoffs, with the Braves representing the biggest underdogs at +217 in Game 2 against the Dodgers, a game Atlanta won. 

The high-variance sport of baseball is intriguing to wager on when you’re getting underdog prices, especially with a team that’s as uninspiring as the Guardians.

Cleveland averaged just 4.16 runs scored per game this season, 24th in the league and the worst of any playoff team, which includes even the Red Sox.

Chicago is asking Anthony Kay to shut down this Guardians offense, with Sean Burke scheduled to eat the bulk of the innings for the White Sox. 

Burke looked solid for the White Sox for most of the season, posting a 3.34 ERA and not allowing more than a run in three starts against Cleveland.

Cleveland Guardians pitcher Gavin Williams pitches during the first inning against the Kansas City Royals at Kauffman Stadium in Kansas City, Missouri, Friday, Sept. 25, 2026. Getty Images

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The White Sox are “white hot” right now, and while I’ve always been a Williams fan for the Guardians, I think you have to go with the team playing better baseball right now.

Upset pick: the White Sox storm past the Guardians on Monday and put themselves in a position to advance to the ALCS.

PREDICTION: White Sox moneyline (+141, FanDuel) 

Why Trust New York Post Betting

Erich Richter is a brazilian jiu-jitsu blue belt but he has a black belt in MMA betting. During the football season he’s showcased massive profits at The Post in the player prop market the last two seasons. While constantly betting long shots, his return on investment is 30.15 percent since 2022.