Zuffa LLC

Kayla Harrison vs. Amanda Nunes is a highly-anticipated UFC title fight, and Dustin Poirier wonders if the bout will end in a submission for the champion.

Harrison and Nunes were set to collide in early 2026, but the women’s bantamweight titleholder was forced to undergo neck surgery. The procedure was a success, and Harrison is now prepping to meet her former teammate in the UFC 334 co-main event on Nov. 14.

Poirier has worked with both Harrison and Nunes under the American Top Team banner. During a recent edition of “Deep Waters,” the retired UFC lightweight questioned if Harrison can find a way to submit Nunes inside Madison Square Garden in New York City (via MMAJunkie).

“It’s going to come down to the takedowns,” Poirier said. “Can Kayla use her judo and her wrestling to get Amanda down? If she can, I think she’s going to have a lot of success.

“You know, we’ve seen Amanda submitted before. Kayla’s big, strong, good top position, knows how to grapple, but the length and power Amanda has, you can’t prepare for in the female division. You can’t get girls in the gym who can punch like that.”

Harrison last competed back in June 2025, while Nunes hasn’t fought since 2023 after initially retiring from pro MMA competition. Harrison is the betting favorite over a month ahead of UFC 334, but Nunes will look to prove she’s still the gold standard of the women’s 135-pound division.

Going into the event, Harrison is riding a four-fight winning streak and has just one blemish on her pro MMA record. Nunes retired having gone 14-1 in her last 15 outings, which includes wins in the now defunct women’s featherweight division.

Do you think Kayla Harrison can pull off a submission over Amanda Nunes at UFC 334? Join in on the conversation in the comments below.

This article appeared first on BJPENN.COM